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    Breast Cancer Clinical Trials

    CPMC Cancer Services

    Oncology / Cancer Clinical Trials Main Page | Adult Clinical Trials Main Page

    Further protocol information can be found on the links below at ClinicalTrials.gov


    Active Trials

    Title: A Randomized Phase 3 Clinical Trial Evaluating Post-Mastectomy Chestwall & Regional Nodal XRT & Post-Lumpectomy Regional Nodal XRT in Patients With Positive Axillary Nodes Before Neoadjuvant Chemo Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemo
    Description: Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery
    Investigator: NCI - National Cancer Institute
    Eligibility: Female subjects, 18 y/o and older, who have clinically T1-3, N1 breast cancer at the time of diagnosis (before neoadjuvant therapy) and who have had pathologic confirmation of axillary nodal involvement at presentation (before neoadjuvant therapy)
    Status: Please contact site for study status
    Contact: Brenda Eng, 415-600-1775, Email: EngB@cpmcri.org about Study NSABP B-51

    Title: Randomized Double-Blind Placebo Controlled Study of Subcutaneous Testosterone in the Adjuvant Treatment of Postmenopausal Women With Aromatase Inhibitor Induced Arthralgias
    Description: Testosterone in Treating Postmenopausal Patients With Arthralgia Caused by Adjuvant Aromatase Inhibitor Treatment
    Investigator: NCI - National Cancer Institute
    Eligibility: Female subjects, 18 y/o and older, who have undergone a total mastectomy or breast-conserving surgery for primary breast cancer +/-chemotherapy and +/-radiotherapy
    Status: Please contact site for study status
    Contact: Brenda Eng, 415-600-1775, Email: EngB@cpmcri.org about Study Alliance A221102

    Title: A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently With Radiation Therapy and Radiation Therapy Alone for Women With HER2-Positive Ductal Carcinoma In Situ Resected by Lumpectomy
    Description: Radiation therapy with or without Trastuzumab in treating women with ductal carcinoma in situ who have undergone lumpectomy
    Investigator: NCI - National Cancer Institute
    Eligibility: Female subjects, 18 y/o and older, who have a histologically confirmed ductal carcinoma in situ and who have unergone resection by lumpectomy
    Status: Please contact site for study status
    Contact: Brenda Eng, 415-600-1775, Email: EngB@cpmcri.org about Study NSABP B-43

    Title: A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women With Node- Positive or High-Risk Node-Negative HER2-Low Invasive Breast Cancer
    Description: Chemotherapy with or without Trastuzumab after surgery in treating women with invasive breast cancer
    Investigator: NCI - National Cancer Institute
    Eligibility: Female subjects, 18 y/o and older, with a tumor that must be unilateral invasive adenocarcinoma of the breast on histologic examination
    Status: Please contact site for study status
    Contact: Brenda Eng, 415-600-1775, EngB@cpmcri.org about Study NSABP B-47

    Title: Phase III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients With High-Risk, Hormone Receptor-Positive and HER2/Neu Negative Breast Cancer
    Description: S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer
    Investigator: NCI - National Cancer Institute
    Eligibility: Subjects, 18 y/o and older, who have a histologically confirmed diagnosis of invasive breast carcinoma, who have undergone axillary staging. And who have completed either breast-conserving surgery or total mastectomy
    Status: Please contact site for study status
    Contact: Brenda Eng, 415-600-1775, Email: EngB@cpmcri.org about Study SWOG S1207

    • updated April 2014

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