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    Stroke / Neuro Critical Care

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    Further protocol information can be found on the links below at ClinicalTrials.gov


    Active Trials

    Title: Stryker Neurovascular Trevo® Retriever Registry
    Description: The purpose of the Trevo® Retriever Registry is to collect real world performance data of the Trevo Retriever which is intended to restore blood flow in the neurovasculature by removing thrombus in patients experiencing ischemic stroke
    Investigator: Joey English, MD
    Eligibility: Subjects experiencing acute ischemic stroke who are eligible for restoration of blood flow using any approved Trevo Retriever in the neurovasculature to remove thrombus
    Status: Active and open to enrollment
    Contact: Katie Ponting, 415-600-1163, Email: PontinK@cpmcri.org about Study Trevo Retriever

    Title: Diffusion Weighted Imaging (DWI) or Computerized Tomography Perfusion (CTP) Assessment With Clinical Mismatch in the Triage of Wake Up and Late Presenting Strokes Undergoing Neurointervention
    Description: The purpose of the study is to evaluate the hypothesis that Trevo thrombectomy plus medical management leads to superior clinical outcomes at 90 days as compared to medical management alone in appropriately selected subjects experiencing an acute ischemic stroke when treatment is initiated within 6-24 hours after last seen well.
    Investigator: Joey English, MD
    Eligibility: Subjects 18 years of age and older with clinical signs and symptoms consistent with the diagnosis of an acute ischemic stroke
    Status: Coming soon
    Contact: Katie Ponting, 415-600-1163, Email: PontinK@cpmcri.org about Study DAWN

    Title: Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial
    Description: A multicenter, randomized, controlled clinical trial of 1400 patients that will include approximately 60 enrolling sites. The study hypotheses are that treatment of hyperglycemic acute ischemic stroke patients with targeted glucose concentration (80mg/dL - 130 mg/dL) will be safe and result in improved 3 month outcome after stroke
    Investigator: Nobl Barazangi, MD
    Eligibility: Subjects, 18 years of age and older, must be within 12 hours of stroke symptom onset and have diabetes and glucose concentrations of over 110 mg/dL on initial evaluation
    Status: Active and open to enrollment
    Contact: Katie Ponting, 415-600-1163, Email: PontinK@cpmcri.org about Study SHINE

    Title: A Phase 2 Double Blinded, Randomized, Placebo Controlled Dose Escalation Study to Evaluate the Efficacy and the Safety of GM602 in Patients With Acute Middle Cerebral Artery Ischemic Stroke Within an 18-hour Treatment Window
    Description: Efficacy and Safety Study of GM602 in Patients With Acute Middle Cerebral Artery Ischemic Stroke Within 18 Hours (GMAIS)
    Investigator: Nobl Barazangi, MD
    Eligibility: Subjects with Acute Middle Cerebral Artery Ischemic Stroke who can be treated within an 18-hour treatment window
    Status: Active and open to enrollment
    Contact: Katie Ponting, 415-600-1163, Email: PontinK@cpmcri.org about Study GMAIS

    Title: Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial
    Description: Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial
    Investigator: Nobl Barazangi, MD
    Eligibility: 18 years of age and older with the ability to randomize within 12 hours of symptom onset
    Status: Active and open to enrollment
    Contact: Katie Ponting, 415-600-1163, Email: PontinK@cpmcri.org about Study POINT

    Title: Expanding the Time Window for IV Thrombolysis with rt-PA in Acute Ischemic Stroke Patients Using Computed Tomography Perfusion Imaging: The PERFusion Use in Stroke Evaluation (PERFUSE) Study
    Description: Patients with ischemic stroke who can be treated within six hours of symptom onset
    Investigator: Nobl Barazangi, MD
    Eligibility: Acute Ischemic Stroke (AIS) patients, ≥ 18 years old, who present up to 6 hours from time of onset of acute stroke symptoms
    Status: Active and open to enrollment
    Contact: Katie Ponting, 415-600-1163, Email: PontinK@cpmcri.org about Study PERFUSE

    • updated September 2014

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