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    California Pacific Currents 2003

    Currents 2003 Table of Contents | Currents Main Page

    Federal Funding  |  State Funding  |  Foundation Funding  |  Pharmaceutical and Biotechnology Funding  |  Investigator Initiated

    New Research Funding for California Pacific Investigators

    Federal Funding

    • Mary Abood, PhD: Molecular Mechanisms of Cannabinoid Receptor Regulation; Anendamide Receptors: Role In Motor Neuron Production

    • John Astin, PhD: Barriers to Integration of Mind Body Medicine

    • Warren Browner, MD, MPH: Potassium Citrate, Thiazides, or Combination to Prevent Bone Loss

    • Steven Cummings, MD: Sex Hormones and Genetic Risk Factors for Hip Fractures (Women's Health Initiative)

    • Robert Debs, MD: Identifying Genes that Cause Progression of Lung Cancer

    • Gordon Fung, MD: Chinese Community Smoking Cessation Project

    • Robert Gish, MD: Lamivudine and Intramuscular Hepatitis B Immune Globulin versus Lamivudine Monotherapy as Maintenance Prophylaxis against Recurrent Hepatitis B Post Transplantation in High-Risk Patients; Observational Database of Patients Who Receive Orthotopic Liver Transplantation for Hepatitis B

    • Eric Goldman, MD: AIDS and Cancer Specimen Resource Central Operations and Data Coordinating Center

    • Kenneth Laxer,MD: Neurolmaging in Epilepsy

    • Robert Mille, MD: Macrophage Infiltration of Organ Tissue in Patients with Amyotrophic Lateral Sclerosis (ALS): A Post-MortemStudy; Placebo-Controlled,Double-Blinded Trial of Minocycline in Patients with ALS

    • Dan Moore, PhD: Cancer Center Support Grant; Support of Continuous Research (SCOR) on Sex and Gender Factors Affecting Women's Health

    • Marsha Nunley, MD: Care Preferences for People Living with Serious Illness

    • Marilyn SchIltz, PhD: Distant Healing Placebo Effects in Surgical Wound Healing

    • Lowell Young, MD: Drug Development for Opportunistic Infections

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    State Funding

    • Shanaz Dairkee, PhD: Infinite Expansion of Breast Tumor Samples in Culture

    • Robart Debs, MD: Molecular Pathogenesis of Metastatic Breast Cancer

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    Foundation Funding

    • Devron Char, MD: Ocular Cancer Study

    • Ellen Levine, PhD, MPH: Effects of Compassionate/Loving Intention as a Therapeutic Intervention by Partners of Breast Cancer Patients: A Randomized Controlled Trial

    • Robert Miller, MD: Magnetic Resonance Studies of Metabolites In the Human Brain at 4 Telsa

    • Dean Omish, MD: The Beverage Study ll

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    Pharmaceutical and Biotechnology Funding

    • Ari Baron, MD: Symptom Burden in Subjects with Nonmyeloid Malignancies Receiving Chemotherapy and Aranesp; Safety and Pharmacokinetics of Orally Administered Gallium Maltolate in Patients with Various Refractory Malignancies; Docetaxel vs Docetaxel Plus Genasense (Bcl-2 Antisense Oligonucleotide) in Patients with Previously Treated Non-Small Cell Lung Cancer; Docetaxel Plus DN-101. or Placebo in Androgen Independent Prostate Cancer; Influence of Hepatic Dysfunction on Safety, Tolerability and Pharmacokinetics of PTK787ZJ(222584 in Patients with Unresectable Hepatocellular Carcinoma

    • Steven Becker, MD: Loplnavir/Ritonavir in Combination with Saquinavir Mesylate or Lamivudine/Zidovudine to Explore Metabolic Toxicities in Antiretroviral Naive HIV-Infected Subjects; Immunologic Correlates of Responses to an Initial Regimen of Nevirapine and Lamivudine/Zidovudine/Abacavir in Patients with Advanced HIV who are Atiretroviral Naive

    • Kenneth Binmoeller, MD: Treatment of Gastric Varices with Cyanoacrylate Glue (Dermabond): An Efficacy, Safety and Cost Utilization Study; The Clinical Utility of Endoscopic Ultrasound in Upper Abdominal Pain

    • Neal Birnbaum, MD: Finding Drugs Active against SLE (Lupus) by Testing Chemical Compounds for Their Ability to Suppress Autoantibody Formation by Patients' Leukocytes

    • Maurizio Bonacini, MD: Safety of Adding Entecavir to Lamiwdine Therapy in HIV and HBV Co-infected Patients Who Have Hepatitis B Viremia while on Lamivudine Treatment

    • Michael Borah, MD: Efficacy and Safety of an Oral Calcimimetic Agent (AMG073) when Two Different Vitamin D Regimens Are Used in Subjects with Secondary Hyperparathyroidism of End-State Renal Disease

    • Bruce Brent, MD: Can Rapid Stratification of Unstable Angina Suppress Adverse Outcomes with Early Implementation of the ACC/AHA Guidelines: The Crusade National Quality Improvement Initiative; Value of Primary Angioplasty after Combination Therapy or Eptifibatide Monotherapy in Acute Myocardial Infarction
    • Natalie Bzowej, MD: Long-Term Safety and Tolerability of Tegaserod in Patients with Symptoms of Functional Dyspepsia; Telbivudine versus Lamivudine in Adults with Compensated Chronic Hepatitis B; Fibrosis Progression Risk in HCV Infected Patients; Efficacy and Safety of Pravastatin 80mg Administered Once Dally to Hypercholesterolemic Subjects with Chronic, Well Compensated Liver Disease; Interferon Treatment Response Study: Genotyping and mRNG Profiling of HCV Patients; Genotyping HCV Patients with Prior and Known Outcome to Interferon Therapy

    • Devron Char, MD: Amniotic Membrane versus Autologous Buccal Membrane Graft after Resection and Treatment of Conjunctival Malignancy

    • Steven Cummings, MD: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safety and Efficacy of an Ultralow Dose of Estradiol Given by Continuous Transdermal Administration in the Prevention of Osteoporosis in Postmenopausal Women

    • David Curtis, MD: Efficacy and Safety of BMS•-88667 versus Placebo in Subjects with Active Rheumatoid Arthritis; Efficacy and Safety of BMS-l88667 versus Placebo in Subjects with Active Rheumatoid Arthritis on Background Disease Modifying Anti-Rheumatic Drugs Who Have Failed Anti-Tumor Necrosis Factor Therapy

    • Robart Falla, MD: Prevalence of PiMZ, PiSZ and PiZZ Genotypes in Obstructive Airway Disease

    • Wayne Fung, MD: Safety of Multi-Dose Intravitreal Injections of rhuFab V2 with Verteporfin (Visudyne) Photodynamic Therapy in Subjects with Neovascular Age-Related Macular Degeneration

    • Deborah Gelinas, MD: Donepezil in the Treatment of Huntington's Disease; Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis (ALS); Efficacy and Safety of Exelon (Rivastigmine Tartrate)3-12 mg/day in Patients with Mild to Moderate Alzheimer’s Disease; High Frequency Chest Wall Oscillation to Reduce the Incidence and Duration of Pulmonary Complications in Patients with ALS

    • Robert Gisb, MD: Evaluation of Elecsys HBV Assays on Prospectively Collected Volunteers as Measured by the Roche Diagnostics Elecsys 2010 and Modular Analytics E170 alyzers; Long Term Assessment of Treatment Outcomes with Entecavir and Lamivudine for Chronic Hepatitis B Infection in Patients Who Have Enrolled in PhaseIII Entecavir Trials; Blood and Blood Products for Use in the Development of Hepatitis C Virus Genotyping and Proficiency Testing Panels; PEG-Intron and Rebetol for the Treatment of Subjects with Chronic Hepatitis C Who Failed to Respond to Previous Combination Therapy; Lamivudine and Peri-Operative IV Hepatitis B Immune Globulin in the Prevention of Recurrent Hepatitis B Post Liver Transplantation in Low Risk Patients: A Controlled Study Comparing the Survival of Patients with Unresectable Hepatocellular Carcinoma (HCC) Treated with THYMITAQ to Patients Treated with Doxorubicin; Durability of Seroconversion in Patients with Chronic Hepatitis B Virus Infection; Adefovir Dipivoxil in the Treatment of Patients with Lamivudine Resistant Chronic Hepatitis B Who Have Limited Treatment Options; Dose Ranging Study of Viramidine in Combination with Pegasys In Treatment of Naïve Subjects with Chronic Hepatitis C Infection; Safety and Efficacy of HBY/MF59 Alone or in Combination with Lamiwdine In Adults with Chronic Hepatitis B Infection; PEG-Intron as Maintenance Therapy versus an Untreated Contrall Group in Adult Subjects with Compensated Cirrhosis; PEG-Intron Maintenance Therapy versus an Untreated Control Group for Prevention of Fibrosis In Adult Subjects with Chronic Hepatitis C with Hepatic Fibrosis; Safety, Tolerability and Pharmacokinetics of Hepavir B In Adult Subjects with Compensated Hepatitis B Virus Infection; Safety, Tolerability and Pharmacokinetics Study of a Caspase Inhibitor, IDN-8S58, in Patients with Liver Impairment

    • Michael Katz, MD: Transvaginal Placement of Abdominal Cerclage: A New Approach

    • Kanneth Laxer, MD: Safety and Efficacy of Levetiracetam in the Adjunctive Treatment of Adult Female Subjects (18-40 Years of Age) with C1 Catamenial Epilepsy

    • Kathleen Lewis, MD: Clinical Comparison Study of the Natus A1 go Newborn Hearing Investigational Screener with the Algo Newborn Hearing Screener (Natus Medical, Inc.PC000025)
      Suzanne Li, MD: Safety and Efficacy of AL6221 Compared to XALATAN Dosed Once Daily in Japanese Subjects with Open Angle Glaucoma or Ocular Hypertension

    • Robert Osorio, MD: Evaluation of Conversion from Calcineurin Inhibitor Treatment to Sirolimus Treatment versus Continued Calclneurin Inhibitor Treatment in Liver Allograft Recipients Undergoing Maintenance Therapy; Evaluation of the VitaGen Extracorporeal Liver Assist Device System in the Management of Patients with Fulminant Hepatic Failure; A Retrospective Analysis of the Ten-Year Patient Outcomes from the Randomized, Multi-Center Trial Comparing the Use of Prograf and
      Cyclosporine in Primary Liver Transplant

    • Marilyn Robertson, MD: A Phase III, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Fixed Dose Response Study Comparing the Efficacy and Safety of Sumanirole versus Placebo in Patients with Early Parkinson's Disease

    • William Snape Jr., MD: Human Anti-Tumor Necrosis Factor (Anti-TNF) Monoclonal Antibody for the Induction of Clinical Remission in Subjects with Crohn's Disease; Efficacy of Treatment with Tegaserod and Placebo in Female Patients with Irritable Bowel Syndrome with Constipation; Effect of Lansoprazole versus Esomeprazole on Healing and Symptom Relief in Subjects with Erosive Esophagitis; Efficacy of GM-611 in Patients with Diabetic Gastroparesis; Gastric Stimulation for Vomiting, Nausea and Related Symptoms Associated with Gastroparesis Using the Enterra Gastric Stimulation System

    • Kevin Stone, MD: Reconstruction of Ruptures of Anterior Cruciate Ligament Utilizing the Z-Lig Device

    • Ed Wakil, MD: Emtricitabine for the Treatment of Chronic Hepatitis B Virus Infection; Safety and Efficacy of Human HCV-Antibody (HCV-Ab68) for Prevention of Hepatitis C Disease Recurrence in Patients Who Received Hepatic Allografts for Treatment of End-Stage Liver Disease Due to Hepatitis C Virus Infection

    • Li-Xi Yang, MD, PhD: Synthesis and Scale-Up of Chemicals

    • Alex Zapolanski, MD: Safety and Performance of the Sutureless Anastomotic System for Creating Coronary Anastomoses

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    Investigator Initiated

    • Rudolf Bumlc, MD: Evaluation of Circulation in Replanted Parts and Elective Microvascular Surgery

    • Deborah Gelinas, MD: Nutritional Properties of the Herbal Dietary Supplement QR-334 for Subjects with Excessive Salivary Secretions Dobri Kiprov, MD: Cellular Immunotherapy for the Treatment of Cancer and HIV

    • Alan Kramer, MD: Treating Non-Small Cell Lung Cancer with IRESSA: The CPMC Experience

    • John Mendelson, MD: Web Survey of Use of the Legal Inebriating Herb Salvia Divinorum

    • Lany Scherwttz, PhD: Improving Patient Satisfaction in the Ambulatory Surgery Unit

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