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    Causes and Signs of Kidney Disease

    Most kidney diseases affect the nephrons, causing them to lose their filtering capacity. Frequently, kidney diseases slowly destroy the nephrons without any signs of damage for a long period of time. Nearly all diseases impact both kidneys at the same time.

    Kidney disease can be autoimmune, infection-related, hereditary, or occur as a result of poisons or trauma. However, the two most common causes of kidney disease are diabetes and high blood pressure.

    People in the early stages of kidney disease usually have no symptoms. As the disease worsens, the person may have the following symptoms:

    • The need to urinate more or less often than usual

    • Feeling tired

    • Itchy

    • Loss of appetite or nausea and vomiting

    • Swollen hands and feet or numbness

    • Drowsiness or trouble concentrating

    • Skin darkening

    • Muscle cramps
    A kidney transplant might be a treatment option for someone whose kidneys have stopped working.

    About California Pacific Medical Center

    California Pacific Medical Center, part of the Sutter Health network, offers kidney, pancreas, liver and heart transplantation as part of our Barry S. Levin, MD Department of Transplant.

    Kidney & Pancreas Transplant Program
    California Pacific Medical Center
    2340 Clay Street
    San Francisco, CA 94115
    Tel. 415-600-1700

    Outreach locations available throughout Northern California and in Reno.